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What are Electronic Pills and their Applications?


Electronic Pills

We are familiar with a wide range of sensors in the field of electronics. They are used widely in the various experiments research activities too. This microelectronic pill is such a sensor with a number of channels and is called as a multichannel sensor. As the name implies, this sensor is a pill. That is it meant to go inside the body and to study the internal conditions.

Earlier it was when the transistor was invented, that radiometry capsules were first put into use. These capsules made use of simple circuits for studying the gastrointestinal tract. Some of the reasons that prevented their use were their size and their limitation of not to transmit through more than a single channel. They had poor reliability and sensitivity.

The lifespan of the sensors was also too short. This paved the way for the implementation of single-channel telemetry capsules and they were later developed to overcome the demerits of the large size of laboratory type sensors.

The semiconductor technologies also helped in the formation and thus finally the presently seen microelectronic pill was developed. These pills are now used for taking remote biomedical measurements in researches and diagnosis. The sensors make use of the microtechnology to serve the purpose. The main intention of using the pill is to perform an internal study and recognize or detect the abnormalities and the diseases of the gastrointestinal tract. In this GI (Gastro-Intestinal) tract we cannot use the old endoscope as the access is restricted.

 

BLOCK DIAGRAM

The design of the microelectronic pill is in the form of a capsule. The encasing it has is biocompatible. Inside this are multi-channel (four channels) sensors and a control chip. It also comprises a radio transmitter and two silver oxide cells. The four sensors are mounted on the two silicon chips. In addition to it, there are a control chip, one access channel and a radio transmitter.

The four sensors commonly used are a temperature sensor, pH ISFET sensor, a dual-electrode conductivity sensor, and a three electrode electrochemical oxygen sensor.

Microelectronic pill consists of 4 sensors (2) which are mounted on two silicon chips (Chip 1 & 2), a control chip (5), a radio transmitter (STD- type1-7, type2-crystal type-10), silver oxide batteries (8), 1-access channel, 3-capsule, 4- rubber ring, 6-PCB chip carrier.

The microelectronic pill consists of a machined biocompatible (non-cytotoxic), chemically resistant polyether-terketone (PEEK) capsule and a PCB chip carrier acting as a common platform for attachment of sensors, ASIC, transmitter & batteries. The fabricated sensors were each attached by wire bonding to a custom made chip carrier made from a 10pin, 0.5pitch polymide ribbon connector.

The connector in turn was connected to an industrial STD, flat cable plug (FCP) socket attached to the PCB carrier chip of the microelectronic pill, to facilitate the rapid replacement of the sensors when required. The PCB chip carrier was made from 2 STD. 1.6 mm-thick fiberglass boards attached back to back epoxy resin which maximized the distance between the 2 sensor chips.

The sensor chips are connected to both sides of the PCB by separate FCP sockets, with sensor chip 1 facing the top face, with the sensor chip 2 facing down. Thus, the oxygen sensor on chip 2 had to be connected to the top face by three 200nm copper leads soldered onto the board. The transmitter was integrated in the PCB which also incorporated the power supply rails, the connection points to the sensors, as well as the transmitter & the ASIC & the supporting slots for the capsule in which the carrier is located.

 

There are basically 4 sensors mounted on two chips- Chip 1 & chip 2. On chip 1

There are basically 4 sensors mounted on two chips- Chip 1 & chip 2. On-chip

1. Sensor chip 1

An array consisting of both temperature sensor & pH sensor platforms was cut from the wafer and attached to 100-µm- thick glass coverslip cured on a hot plate. The plate acts as a temporary carrier to assist handling of the device during level 1 of lithography when the electric connection tracks, electrode bonding pads are defined. Bonding pads provide electrical contact to the external electronic circuit.

Chip 1 is divided into two- LHS unit having the temperature sensor silicon diode, while the RHS unit comprises the pH ISFET sensor.

DT-670-SD Silicon Diode Features

  • It measures the body core temperature.
  • Also compensates with the temperature induced signal changes in other sensors.
  • It also identifies local changes associated with tissue inflammation & ulcers.

 

ISFET:

Ion Selective Field Effect Transistor ISFET; this type of electrode contains a transistor coated with a chemically sensitive material to measure pH in solution and moist surfaces. As the potential at the chemically active surface changes with the pH, the current induced through the transistor varies. A temperature diode simultaneously monitors the temperature at the sensing surface. The pH meter to a temperature compensated pH reading correlates the change in current and temperature.

2. Sensor chip 2

The Level 1 pattern (electric tracks, bonding pads, and electrodes) was defined in 0.9µm UV3 resist by electron beam lithography. A layer of 200nm gold (including an adhesion layer of 15nm titanium and 15nm palladium) was deposited by thermal evaporation. The fabrication process was repeated.

Oxygen sensor detection principle

Most portable or survey instruments used for workplace evaluation of oxygen concentrations make use of “fuel cell” type oxygen sensors. “Fuel cell” oxygen sensors consist of a diffusion barrier, a sensing electrode (cathode) made of a noble metal such as gold or platinum, and a working electrode made of a base metal such as lead or zinc immersed in a basic electrolyte (such as a solution of potassium hydroxide).

Control Chip

ASIC (Application-Specific Integrated Circuit) is the control chip that connects together the external components of the microsystem.

Interfacing of ASIC with external components of the system
Figure 8: Interfacing of ASIC with external components of the system

 Application-Specific Integrated Circuit (ASIC)

An integrated circuit designed to perform a particular function by defining the interconnection of a set of basic circuit building blocks drawn from a library provided by the circuit manufacturer.

ASIC is a novel mixed-signal design that contains an analog signal conditioning module operating the sensors, 10-bit ADC & DAC converters & a digital data processing module. An RC relaxation oscillator (OSC) provides the clock signal.

The analog module is based on the AMS (Automated Manifest System), which offer a lot of power saving scheme (sleep mode) & a compact IC design. The temperature circuitry biased the diode at a constant current so that a change in temperature would result in the corresponding change in diode voltage.

The pH ISFET sensor was biased as a simple source & drain follower at constant current with D-S voltage changing with threshold voltage & pH. Conductivity circuit operated at direct current measuring the resistance across the electrode pair as an inverse function of solution conductivity. An incorporated potentiostat operated the amperometric oxygen sensor with a 10-bit DAC controlling the working electrode potential with respect to the reference.

The analog signals were sequenced through a MUX prior to being digitized by the ADC. The bandwidth for each channel was limited by the sampling interval of 0.2ms.

Radio Transmitter

It’s assembled prior to integration in the capsule using discrete surface mount components on a single-sided PCB. The footprint of the standard transmitter measured 8*5*3mm including the integrated coil (magnetic) antenna. It’s designed to operate at a transmission freq. of 40.01MHz at 20˚C generating a signal of 10kHz bandwidth. A second crystal stabilized transmitter was also used. This unit is similar to the free running STD transmitter, having a transmission frequency limited to 20.08MHz at 20˚C, due to crystal used. Pills incorporating the STD transmitter are Type 1, whereas the pills having crystal stabilized unit is Type 2. The transmission range was measured as being 1m & the modulation scheme FSK (Frequency Shift Keying), with a data rate of 1kb/s.

ADVANTAGES

  • It is being beneficially used for disease detection & abnormalities in the human body. Therefore, it is also called a MAGIC PILL FOR HEALTH CARE.
  • Adaptable for use in corrosive & quiescent environment.
  • Micro Electronic Pill utilizes a PROGRAMMABLE STANDBY MODE, So power consumption is very less.
  • It has a very small size, hence it is very easy for practical usage.
  • High sensitivity, Good reliability & Lifetimes.
  • A very long life of the cells (40 hours), Less Power, Current & Voltage requirement (12.1mW, 3.9mA, 3.1 V).
  • Less transmission length & hence has zero noise interference

APPLICATIONS

  • Environmental & industrial applications, such as the evaluation of water quality, pollution detection, fermentation process control & inspection of the pipelines.
  • The integration of radiation sensors
  • The application of indirect imaging technologies such as ultrasound & impedance tomography.
  • Improve the detection of tissue abnormalities
  • Radiation treatment associated with cancer & chronic inflammation.   

 

Summary
What are Electronic Pills and their Applications?
Article Name
What are Electronic Pills and their Applications?
Description
This microelectronic pill is such a sensor with a number of channels and is called as a multichannel sensor. As the name implies, this sensor is a pill. That is it meant to go inside the body and to study the internal conditions.
Author
Tamilsevi
Publisher Name
IPCS Automation Coimbatore
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Studying at IPCS had been a really good experience for me. The teaching faculty were really helpful. They always backed me when i was into some sort of trouble. Although the beginning was very difficult, as time went by i got experience and became easy and i started solving problems myself.

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Hi, Iam Muhammed Shabir studying IPCS Trivadrum in CCTV security system. good teaching very nice class. Iam very satisfied this... Read All

CCTV Security System Training Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T09:07:49+00:00

CCTV Security System Training Trivandrum, Kerala

Hi, Iam Muhammed Shabir studying IPCS Trivadrum in CCTV security system. good teaching very nice class. Iam very satisfied this course

Sakeer Saleem – CCTV Security System Trivandrum, Kerala

Hai, I am Sakeer s study CCTV security System in IPCS Trivandrum. absolutely outstanding teaching and relationship in IPCS Trivandrum.... Read All

CCTV Security System Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T09:15:51+00:00

CCTV Security System Trivandrum, Kerala

Hai, I am Sakeer s study CCTV security System in IPCS Trivandrum. absolutely outstanding teaching and relationship in IPCS Trivandrum. It was a nice experience to study at IPCS. The training center has good facilities is well equipment's.

Aneesh Kumar – CCTV Security System Trivandrum, Kerala

My name is Aneesh Kumar and am studying CCTV security system in IPCS Trivandram.. I really appreciate the teaching and... Read All

CCTV Security System Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T09:34:06+00:00

CCTV Security System Trivandrum, Kerala

My name is Aneesh Kumar and am studying CCTV security system in IPCS Trivandram.. I really appreciate the teaching and provided faculties..the training program is exellent generally the instructors are excellent..it was great experience to study in IPCS.......

Maheen Khan – CCTV Security System Training Trivandrum, Kerala

I have completed my CCTV SECURITY SYSTEM from IPCS Trivandrum branch. Excellent training with well industrial experienced faculties. Well supportive... Read All

CCTV Security System Training Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T09:54:34+00:00

CCTV Security System Training Trivandrum, Kerala

I have completed my CCTV SECURITY SYSTEM from IPCS Trivandrum branch. Excellent training with well industrial experienced faculties. Well supportive staffs. Completely job oriented training. I've got job in Dubai. Thanks to IPCS

Arshad Najeeb Khan – Automation Training Kollam, Kerala

IPCS is more useful for job seekers then teachers are more helpful in each part of the courses and internship... Read All

Automation Training Kollam, Kerala

HalGatewood.com Plugins
4.0
2018-05-28T09:59:47+00:00

Automation Training Kollam, Kerala

IPCS is more useful for job seekers then teachers are more helpful in each part of the courses and internship are available in course completion students and i am proud to be an Ipcsian

Ajish Ashok – Automation Training Trivandrum, Kerala

Excellent Training Center. Joined here for automation course after M.Tech, and work experience. Good faculty and it is highly job... Read All

Automation Training Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T11:20:08+00:00

Automation Training Trivandrum, Kerala

Excellent Training Center. Joined here for automation course after M.Tech, and work experience. Good faculty and it is highly job oriented training. Best part is they will provide you with numerous job interviews after the training program, so that you can chose as per your own interest.

Akhil G S – Automation Training Trivandrum, Kerala

Faculties are brilliant and helpful.I am readily satisfied with IPCS.

Automation Training Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T11:48:56+00:00

Automation Training Trivandrum, Kerala

Faculties are brilliant and helpful.I am readily satisfied with IPCS.

Joy Ouseph – Automation, CCTV and security system Trivandrum, Kerala

Institution is leading to automation expertise for real time scenario....it is best for CCTV and security system

Automation, CCTV and security system Trivandrum, Kerala

HalGatewood.com Plugins
4.0
2018-05-28T11:52:41+00:00

Automation, CCTV and security system Trivandrum, Kerala

Institution is leading to automation expertise for real time scenario....it is best for CCTV and security system

Vishnu Vdev V – Automation Placements Trivandrum, Kerala

Good plc training providers in Trivandrum. Much helpful training for getting jobs in automation field. Placement options offered is also... Read All

Automation Placements Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T11:56:03+00:00

Automation Placements Trivandrum, Kerala

Good plc training providers in Trivandrum. Much helpful training for getting jobs in automation field. Placement options offered is also good.

Harikrishnan S – Automation Placements Alappuzha, Kerala

Good training,excellent faculties

Automation Placements Alappuzha, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T11:59:30+00:00

Automation Placements Alappuzha, Kerala

Good training,excellent faculties

Devika Mohanan Pillai – BMS Training Trivandrum, Kerala

The faculty and infrastructure in IPCS automation is very good I would especially like to appreciate the method of teaching... Read All

BMS Training Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T12:24:58+00:00

BMS Training Trivandrum, Kerala

The faculty and infrastructure in IPCS automation is very good I would especially like to appreciate the method of teaching .i will recommend my friends for their BMS training in IPCS

Arunraj M S – PLC Programming & Control Panel Designing at EG&G Riyadh, Saudi Arabia

Got job in EG & G Saudi Arabia. Thanks to IPCS Trivandrum. Thanks for providing excellent training in PLC programming... Read All

PLC Programming & Control Pannel Designing at EG&G Riyadh, Saudi Arabia

HalGatewood.com Plugins
4.0
2018-05-28T12:50:17+00:00

PLC Programming & Control Pannel Designing at EG&G Riyadh, Saudi Arabia

Got job in EG & G Saudi Arabia. Thanks to IPCS Trivandrum. Thanks for providing excellent training in PLC programming and control panel designing.

Anoop S – Automation system engineer Calicut, Kerala

A good plc automation and robotics training centre. Faculties are more supportive and excellent training providers.

Anoop S - Automation system engineer Calicut, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T12:54:05+00:00

Anoop S - Automation system engineer Calicut, Kerala

A good plc automation and robotics training centre. Faculties are more supportive and excellent training providers.

Shaza Mol – Automation & PLC Training Trivandrum, Kerala

Best training center for automation and PLC training. Good lab facilities and machinery. I Like , Thank you IPCS.

Shaza Mol - Automation & PLC Training Trivandrum, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T12:56:39+00:00

Shaza Mol - Automation & PLC Training Trivandrum, Kerala

Best training center for automation and PLC training. Good lab facilities and machinery. I Like , Thank you IPCS.

Maneesh Mathew Koshy – Automation Engineer Kollam, Kerala

Having very good experience in IPCS. Friendly staffs , clarifying doubts.Good study environment

Automation Engineer Kollam, Kerala

HalGatewood.com Plugins
5.0
2018-05-28T12:59:35+00:00

Automation Engineer Kollam, Kerala

Having very good experience in IPCS. Friendly staffs , clarifying doubts.Good study environment

Benyameen Anna – Automation Engineer Ghana

Very good coaching with practice

Automation System Engineer Ghana

HalGatewood.com Plugins
5.0
2018-05-28T14:52:50+00:00

Automation System Engineer Ghana

Very good coaching with practice

Sreejith Mohan – BMS & CCTV Security System Training Thrissur, Kerala

Best BMS training and cctv training. I liked it.

BMS & CCTV Security System Training Thrissur, Kerala

HalGatewood.com Plugins
5.0
2018-05-29T06:56:37+00:00

BMS & CCTV Security System Training Thrissur, Kerala

Best BMS training and cctv training. I liked it.

Risin Samuel – Automation System Engineer Trivandrum, Kerala

It's was good experience to be a part of IPCS Trivandrum.

Automation System Engineer Trivandrum, Kerala

HalGatewood.com Plugins
4.0
2018-05-29T06:58:52+00:00

Automation System Engineer Trivandrum, Kerala

It's was good experience to be a part of IPCS Trivandrum.

Suriya Krishna – Programming and industrial Automation Training Dubai, UAE

Best Institution for Designing, Programming and industrial Automation. International standards and certified institutions all over the globe. Happy to say... Read All

Programming and industrial Automation Training Dubai, UAE

HalGatewood.com Plugins
5.0
2018-05-29T07:10:12+00:00

Programming and industrial Automation Training Dubai, UAE

Best Institution for Designing, Programming and industrial Automation. International standards and certified institutions all over the globe. Happy to say i have chosen a right institution for Automation Course.

Anil Mohan – Automation Engineer Dubai, UAE

This place helped me a lot to improve my skills on automation by giving the real industrial exposure . excellent... Read All

Automation Engineer Dubai, UAE

HalGatewood.com Plugins
5.0
2018-05-29T07:22:35+00:00

Automation Engineer Dubai, UAE

This place helped me a lot to improve my skills on automation by giving the real industrial exposure . excellent lab facilities and good training methodologies

Srinivas B – Automation System Engineer Dubai, UAE

Excellent faculty and excellent teaching facilities. Almost all the brands available for hands on training . 100 % Individual attention... Read All

Automation System Engineer Dubai, UAE

HalGatewood.com Plugins
5.0
2018-05-29T07:56:38+00:00

Automation System Engineer Dubai, UAE

Excellent faculty and excellent teaching facilities. Almost all the brands available for hands on training . 100 % Individual attention .
4.8
58

WORKSHOPS [ 2 - 5 DAYS ]

  • Corporate Companies
  • Working Professionals
  • Education Institutions

IPCS AUTOMATION TRAINING INSTITUTE

IPCS Automation research oriented Training Institute, Providing job oriented training & Government, International certification with 100% placements. IPCS Automation Authorized training center for PLC Training, automation Training, corporate Training, Marine Automation, Process Control Automation, Machine Automation, Industrial Automation, Building Management System Training, SCADA Training, DCS Training, HMI Training, VFD Training, CCTV & Security System Training, BMS Training, Control Panels Designing Training, Calibration Training, EMBEDDED Training.

IPCS AUTOMATION TRAINING INSTITUTE

IPCS Automation research oriented Training Institute, Providing job oriented training & Government, International certification with 100% placements. IPCS Automation Authorized training center for PLC Training, automation Training, corporate Training, Marine Automation, Process Control Automation, Machine Automation, Industrial Automation, Building Management System Training, SCADA Training, DCS Training, HMI Training, VFD Training, CCTV & Security System Training, BMS Training, Control Panels Designing Training, Calibration Training, EMBEDDED Training.

Automation Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

PLC Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

SCADA Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

VFD Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

DCS Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

HMI Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

Electric Control Panel Designing Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

Process Control Automation Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

Automation Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

Automation Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

Automation Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

Automation Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe

Automation Training: India | Mumbai | Kerala | Cochin | Calicut | Trivandrum | Tamil Nadu | Coimbatore | Chennai | UAE | Saudi Arabia | Qatar | Singapore | Malaysia | Africa | Nijeria | Ghana | Sudan | Zimbabwe